DIABETIC KETOACIDOSIS WITH OLD MI

25year old male painter by occupation since 8  years came tocasuality on 7/2/23 with complaints of

c/o fever,vomitings,constipation since 1 week

C/ o chest pain, palpitations since 1 week

C/o sob since 1week

c/o neck pain

History of present illness

Patient was apparently asymptomatic 9 years back,

Patient c/o blurring of visionin right eye for which he went to local hospital used medication eye drops(Rt>>Lt) wasn't subsided 

In 2014 patient c/o severe weight loss approximately 10-12 kgs over a duration of 2 months. And having increased appetite, increased frequency of urination with these complaints he went to Local hospital and diagnosed with type 1 diabetes mellitus and since then he was started on Mixtard insulin 28U -x - 24U and since then he is on regular follow up..

24u- x-20u now he was using

 His fbs used to be around 200-250 and ppbs around 250-300

Last HbA1c was 11.2 on feb 3rd 

Now since 1 week patient had a fever whichwas sudden in onset high grade associated with chills and rigor , no diurnal variations

C/ O vomitings 2- 3 episodes / day, non bilious non projectile food particles as content

C/ o short ness of breath on exertion which was sudden in onset gradually progressive no aggrevating and relieving factors

C/ o abdominal pain, nausea, decreased appetite

C/o constipation

C/o dry ness of mouth

C/ o neck pain which was throbbing type 


 c/o chest pain, on left side non radiating, pricking type

Palpitations, no syncopal attacks, 

No h/ o altered sensorium

No meningeal signs 

Past history:

K/c/o type 1 Dm since 9 years 


History of injury to left foot 6 months ago on plantar aspect due to prick by thorn while walking on a bare foot associated with swelling and pus discharge non blood stained for which he consulted local doctor excision was done and he was put on antibiotics followed by regular dressings for amonth.

Resonant note heared,no obliteration on traubes space

Auscultation ; 

BAE-PRESENT, 

Per abdomen:

Per abdomen;

Shape; scaphoid
Umbilicus; central
Movements ; normal
No visible pulsations or engorged veins,no visible peristalsis
Skin over abdomen ;normal
Palpation; soft non tender,
*  no tenderness,or local rise of temperature
Percussion ;
Liver; resonant note heared
No fluid thrills,shifting dullness
Auscultation;

Bowel sounds are heared


CVS:


Inspection;
Position of trachea ;midline
No visible pulsations,

Precordial bulge : absent
Shape of chest; bilaterally symmetrical
Apex beat ; left 5th inter costal space1cm medial to mid clavicular line
Palpation; no palpable thrills,parasternal heaves are palpable
Percussion ; 
Auscultation; S1,S2 heart sounds are heared , 

CNS:

Higher mental functions intact

Reflexes- present
Power,muscle tone- normal
Gait- normal
No meningeal signs
Cranial nerves - intact

Investigations:

Urine for ketone bodies positive

Ecg : old inferior wall myocardial infarction( leads2,3,Avf)




USG abdomen:

B/l raised echogenicity of kidneys


Abg:

Metabolic acidosis with high anion gap

Anion gap: Na+k - cl + hco3

                   126+4-110+4.5

                  = 130-115.5

                  =15.5


TG:147

Hdl:32

LDL:92.8

Vldl:32.4

Serology: negative


Provisional diagnosis:


Diabetic ketoacidosis with old inferior wall myocardial infarction with k/c/o type 1 diabetes mellitus since 10 years with diabetic nephropathy


Treatment:


Iv fluids ns@ 75ml/ hour

5% dextrose if grbs < 250 mg/dl

Human Actrapid insulin infusion ( 1ml +39 ml ns)@3 ml/ hour based on grbs

Tab ECOSPIRIN 75/75/10 mg / po/HS

Tab Telma 40 po od

Grbs monitering hourly

Input/ output charting

Vitals monitering 2 nd hrly


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